Cerebral small vessel disease impairs dynamic cerebral autoregulation and mediates outcomes after stroke thrombectomy
Yue Qiao, Ran Liu, Lupei Cai, Min Zhao, Boyi Yuan, Siying Fan, Shengjun Wang, Jiameng Li, Longfei Wu, Yingqi Xing, Qingfeng Ma, Wenbo Zhao · 2026
Read Cerebral small vessel disease impairs dynamic cerebral autoregulation and mediates outcomes after stroke thrombectomy by Yue Qiao, Ran Liu, Lupei Cai, Min Zhao, Boyi Yuan, Siying Fan, Shengjun Wang, Jiameng Li, Longfei Wu, Yingqi Xing, Qingfeng Ma, Wenbo Zhao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13424517.txt.
Description
Qiao and colleagues studied in 2026 why small vessel disease in the brain worsens recovery after stroke thrombectomy, the procedure that pulls a clot from a blocked brain artery. They focused on dynamic cerebral autoregulation, the brain's ability to steady its own blood flow, as a possible middle link. The cohort held 107 patients whose blocked front-brain arteries were opened successfully, sorted by small vessel burden on scans.
Qiao measured flow control about a day after treatment and again at four to five days. Patients with mild small vessel disease improved on a key flow measure over that span, while those with heavier burden got worse. Functional independence at 90 days was far commoner in the mild group, at about three quarters against about half. Statistical mediation work credited the flow change with carrying about a quarter of the burden's effect on outcome.
Catalog record
| CREATOR | Yue Qiao, Ran Liu, Lupei Cai, Min Zhao, Boyi Yuan, Siying Fan, Shengjun Wang, Jiameng Li, Longfei Wu, Yingqi Xing, Qingfeng Ma, Wenbo Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |