Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with Ocular Tumours

Pieter A.M. Janssen, Teresa A. Ferreira, T.H. Khanh Vu, Jan-Willem M. Beenakker, Lisa Klaassen · 2026

Read Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with Ocular Tumours by Pieter A.M. Janssen, Teresa A. Ferreira, T.H. Khanh Vu, Jan-Willem M. Beenakker, Lisa Klaassen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13423369.txt.

Description

Janssen and co-authors checked whether two advanced MRI measurements of eye tumors give the same answers when repeated at different hospitals, a requirement before scans can guide diagnosis or judge treatment response. Fifteen patients with uveal melanoma, the most common primary eye cancer in adults, each underwent two scans at two centers.

The repeat scans were separated by a mean interval of 28 days, ranging from 12 to 43 days between visits. Average absolute differences stayed small: 0.07 units on the diffusion measure, 0.11 on relative peak intensity, and 6 percentage points on outflow percentage between the two timepoints. The authors conclude that this variability is smaller than the differences clinicians rely on when distinguishing tumor types or assessing response to radiation, supporting use across centers.

Catalog record

CREATORPieter A.M. Janssen, Teresa A. Ferreira, T.H. Khanh Vu, Jan-Willem M. Beenakker, Lisa Klaassen
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE20 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13423369

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