Emerging Clinical Complications of Alpha-Gal Syndrome: A Scoping Review
Vishnu S Vundamati, Shaan R Patel, Riyana Patel, Nisa Eriskin, Brielle Tila-Cohen, Caiden J Friedrich, Advait Gupta, Raghavee Neupane, Sebastian Arango, Marc M Kesselman · 2026
Read Emerging Clinical Complications of Alpha-Gal Syndrome: A Scoping Review by Vishnu S Vundamati, Shaan R Patel, Riyana Patel, Nisa Eriskin, Brielle Tila-Cohen, Caiden J Friedrich, Advait Gupta, Raghavee Neupane, Sebastian Arango, Marc M Kesselman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13423180.txt.
Description
Vundamati and colleagues reviewed in 2026 the wider health effects of alpha-gal syndrome, an allergy to a sugar found in mammal products. The allergy starts with a lone star tick bite, which primes the immune system against the sugar alpha-gal. The review looked past food reactions to surgery and hospital care, screening 729 records and keeping 14 studies.
Kept studies reported severe allergic reactions not only to foods but also to medical products from mammals. Gelatin, some antibodies, and other surgical ingredients triggered anaphylaxis, a dangerous whole-body reaction, in some patients. Blood transfusions also posed a risk in reported cases. Most evidence came from observational studies in the United States, which limits how far results apply elsewhere. The authors urge surgical and emergency teams to ask about tick-related meat allergy before using mammal-based products.
Catalog record
| CREATOR | Vishnu S Vundamati, Shaan R Patel, Riyana Patel, Nisa Eriskin, Brielle Tila-Cohen, Caiden J Friedrich, Advait Gupta, Raghavee Neupane, Sebastian Arango, Marc M Kesselman |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |