A prospective study for validating an automated AI-based system for detecting age-related macular degeneration in clinical settings
Alauddin Bhuiyan, Arun Govindaiah, Oscar Otero-Marquez, Anna Fabczak-kubicka, Tasin Bhuiyan, Katy Tai, Avnish Deobhakta, Theodore Smith · 2026
Read A prospective study for validating an automated AI-based system for detecting age-related macular degeneration in clinical settings by Alauddin Bhuiyan, Arun Govindaiah, Oscar Otero-Marquez, Anna Fabczak-kubicka, Tasin Bhuiyan, Katy Tai, Avnish Deobhakta, Theodore Smith (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13421544.txt.
Description
Bhuiyan and colleagues report a 2026 trial of an artificial intelligence system that detects age-related macular degeneration, a leading cause of blindness, from photos of the back of the eye. The team enrolled 845 adults over 50 with no prior diagnosis at clinics in New York City. Three eye specialists graded dilated-eye photos as the reference standard.
Judged per patient, the system separated referable disease, meaning more than early disease, from milder states with strong accuracy. It caught about nine in ten referable cases while clearing most healthy ones, scores the authors rate as strong for screening. The photos were taken without dilating drops, so the setup fits routine clinics. A tool like this could flag at-risk patients during ordinary visits and speed referrals, catching disease while steps can still slow its advance toward blindness.
Catalog record
| CREATOR | Alauddin Bhuiyan, Arun Govindaiah, Oscar Otero-Marquez, Anna Fabczak-kubicka, Tasin Bhuiyan, Katy Tai, Avnish Deobhakta, Theodore Smith |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |