Synchronization enhanced force microscopy for clinical tumor tissue mechanical characterization
Jiahao Song, Yanlong Zheng, Xifeng Sun, Yutao Xu, Xianming Qin, Xueyong Wei · 2026
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Description
Song and colleagues report a 2026 engineering study of a tiny force sensor that measures tissue stiffness, a trait that shifts with disease. Standard stiffness tools are bulky or work only outside the body. The team built an all-silicon vibrating sensor that syncs its vibration to sharpen resolution and cut noise without losing sensitivity.
The team tested the sensor on human stomach tissue samples. It picked out clear stiffness gaps between normal tissue, tumor tissue, and scarred fibrotic tissue, three states that can look alike under the eye or camera. The touch stayed gentle and did not damage the samples, so the same tissue could go on to other tests. A small, precise stiffness probe could guide surgeons during keyhole stomach cancer operations, helping them feel, through numbers, where tumor ends and healthy tissue begins.
Catalog record
| CREATOR | Jiahao Song, Yanlong Zheng, Xifeng Sun, Yutao Xu, Xianming Qin, Xueyong Wei |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |