68Ga-FAPI-PET/CT in extra-cervical CUP: Head-to-Head Comparison of 68Ga-FAPI-46 with 18F-FDG in 13 patients
Anna-Maria Spektor, Sergio Armando Zapata Bonilla, Philipp Mildenberger, Anton Kilburg, Daniela Driess, Erik Winter, Michael Kloth, Mathias Schreckenberger, Tobias Bäuerle, Thomas Kindler, Uwe Haberkorn, Maria Pouyiourou, Alwin Krämer, Tilmann Bochtler, Manuel Röhrich · 2026
Read 68Ga-FAPI-PET/CT in extra-cervical CUP: Head-to-Head Comparison of 68Ga-FAPI-46 with 18F-FDG in 13 patients by Anna-Maria Spektor, Sergio Armando Zapata Bonilla, Philipp Mildenberger, Anton Kilburg, Daniela Driess, Erik Winter, Michael Kloth, Mathias Schreckenberger, Tobias Bäuerle, Thomas Kindler, Uwe Haberkorn, Maria Pouyiourou, Alwin Krämer, Tilmann Bochtler, Manuel Röhrich (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13421285.txt.
Description
Anna-Maria Spektor and colleagues compared two PET tracers head to head in 2026 for cancer of unknown primary outside the neck, studying 13 patients who received both scans. Standard glucose PET often fails to find the hidden primary, and fibroblast-targeted FAPI PET had shown promise mainly in head-and-neck-like cases.
Across 21 metastases, neither tracer found more primary tumors, and uptake differences varied by site without a clear overall winner. Oncologists gain a caution that FAPI's edge in head-and-neck-like disease does not automatically extend to extra-cervical unknown-primary cases outside the neck.
Catalog record
| CREATOR | Anna-Maria Spektor, Sergio Armando Zapata Bonilla, Philipp Mildenberger, Anton Kilburg, Daniela Driess, Erik Winter, Michael Kloth, Mathias Schreckenberger, Tobias Bäuerle, Thomas Kindler, Uwe Haberkorn, Maria Pouyiourou, Alwin Krämer, Tilmann Bochtler, Manuel Röhrich |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |