Quantitative 99mTc-PYP SPECT/CT at 90 minutes improves diagnostic stratification in transthyretin cardiac amyloidosis
Tina Nazerani-Zemann, Susanne Stanzel, Friedrich Weitzer, Thomas Kuenzer, Verena Maria Stangl, Jan Bucerius · 2026
Read Quantitative 99mTc-PYP SPECT/CT at 90 minutes improves diagnostic stratification in transthyretin cardiac amyloidosis by Tina Nazerani-Zemann, Susanne Stanzel, Friedrich Weitzer, Thomas Kuenzer, Verena Maria Stangl, Jan Bucerius (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13421186.txt.
Description
Tina Nazerani-Zemann and colleagues tested quantitative SPECT/CT in 2026 for diagnosing transthyretin cardiac amyloidosis, where plain scans often leave borderline cases uncertain. The team added 90-minute quantitative imaging to standard planar scans at 60 and 180 minutes in 170 patients with suspected amyloid heart disease.
Quantitative uptake ratios tracked Perugini scores closely and reclassified more than a third of patients. The biggest gains came in the equivocal middle group, while ratios also tracked heart biomarkers and MRI markers. Cardiologists gain a sharper tool for confirming or ruling out amyloid in the gray zone.
Catalog record
| CREATOR | Tina Nazerani-Zemann, Susanne Stanzel, Friedrich Weitzer, Thomas Kuenzer, Verena Maria Stangl, Jan Bucerius |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |