Palivizumab for Donor‐Derived RSV Infection in an Adult Bilateral Lung Transplant Recipient: A Case Report
Rosemary Meharry, Cassandra Vale, John Mackintosh · 2026
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Description
Rosemary Meharry and colleagues report a lung transplant patient who caught respiratory syncytial virus from the donor organs and kept worsening despite standard care. The adult had received both lungs and faced a rising viral load with deepening breathing failure. Standard antiviral and immune-support treatment failed to turn the course around.
On day 44 after the transplant, the team gave a single dose of palivizumab, an antibody drug normally used to shield infants from this virus. Chest images then improved, viral measures fell, and the virus cleared by day 67 in the timeline reported. Tissue samples had left open whether the lung changes meant infection or rejection, adding to the difficulty. The case shows the antibody can be given safely as a booster to standard care in a profoundly immune-suppressed recipient.
Catalog record
| CREATOR | Rosemary Meharry, Cassandra Vale, John Mackintosh |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 10 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |