Harnessing Exhaled Breath for Lung Cancer Early Detection—Results From the ExPeL Study
Danita Kasi Patel, Leon D'Cruz, Waqar Ahmed, Anoop Chauhan, Nawar Diar Bakerly, Seamus Grundy, Drupad K. Trivedi, Sean Knight · 2026
Read Harnessing Exhaled Breath for Lung Cancer Early Detection—Results From the ExPeL Study by Danita Kasi Patel, Leon D'Cruz, Waqar Ahmed, Anoop Chauhan, Nawar Diar Bakerly, Seamus Grundy, Drupad K. Trivedi, Sean Knight (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13420304.txt.
Description
Patel and colleagues test whether a breath test can flag lung cancer in people attending screening. Most UK screening reaches only those whose risk score qualifies them, and many cancers surface outside that net. Their 2026 ExPeL study collects breath condensate with a device, Inflammacheck. The device reads hydrogen peroxide, a byproduct of inflamed tissue, plus breathing measures. These feed machine learning models trained on clinic patients and low risk ever smoker controls.
Only thirty four participants gave samples, a pilot scale, but four in five cancers were stage one or two, the curable window. The combined model scored well on accuracy and an area under the curve of 0.90, and it raised no false alarms. A chemical scan of the condensate found four molecules that separated cancer from control. Breath testing, the team argues, could one day triage who needs a CT scan first.
Catalog record
| CREATOR | Danita Kasi Patel, Leon D'Cruz, Waqar Ahmed, Anoop Chauhan, Nawar Diar Bakerly, Seamus Grundy, Drupad K. Trivedi, Sean Knight |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |