Coexistence of PYCR1-related cutis laxa and bilateral grade V vesicoureteral reflux with reflux nephropathy: A case report
Dorna Derakhshan, Faizan Bashir, Ali Derakhshan · 2026
Read Coexistence of PYCR1-related cutis laxa and bilateral grade V vesicoureteral reflux with reflux nephropathy: A case report by Dorna Derakhshan, Faizan Bashir, Ali Derakhshan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13420061.txt.
Description
Dorna Derakhshan and colleagues report a 6-year-old girl carrying two rare problems at once: a genetic loose-skin disorder and severe backward flow of urine toward both kidneys. Her skin condition stems from a gene fault that weakens connective tissue across the body. She came to care after repeated fevers from urinary infections, a warning sign that the urinary tract was in trouble.
Scans showed the highest grade of urine reflux on both sides, with the left kidney already small and scarred. Nuclear scans confirmed lasting kidney damage from the backflow. She also showed developmental delay, part of the wider picture her gene condition can bring. The pairing matters because kidney damage can advance quietly while attention stays on the visible skin signs.
Catalog record
| CREATOR | Dorna Derakhshan, Faizan Bashir, Ali Derakhshan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |