Short Echo‐Time Spiral MRSI Versus Single‐Voxel Spectroscopy in the Human Brain at 3 Tesla With Semi‐LASER Localization

Young Woo Park, Isaac M Adanyeguh, Pierre‐Gilles Henry, Dinesh K Deelchand · 2026

Read Short Echo‐Time Spiral MRSI Versus Single‐Voxel Spectroscopy in the Human Brain at 3 Tesla With Semi‐LASER Localization by Young Woo Park, Isaac M Adanyeguh, Pierre‐Gilles Henry, Dinesh K Deelchand (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13419330.txt.

Description

Park and co-authors compared two ways of measuring brain chemistry with magnetic resonance spectroscopy, a scan method that reads chemical signals instead of anatomy. They set a fast spiral imaging technique against the established single-voxel method in the same brain region, the posterior cingulate cortex, in five healthy volunteers at 3 Tesla.

By eye, spectra from the two methods looked comparable in overall quality when scan times were matched exactly. Quantitatively, the imaging method produced a lower signal-to-noise ratio and wider uncertainty bounds on its chemical estimates than the single-voxel scans. Measured levels of glutamate and of glutamate plus glutamine also came out lower with the imaging approach. The team attributes the small gaps to differing tissue weighting and sensitivity, and calls the techniques broadly comparable overall.

Catalog record

CREATORYoung Woo Park, Isaac M Adanyeguh, Pierre‐Gilles Henry, Dinesh K Deelchand
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13419330

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