Baseline versus cumulative cholesterol, high-density lipoprotein, and glucose index and stroke risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: evidence from the CHARLS study
Chen Chen, Xiao Yang, Cheng Li, Qiqi Xi, Yi Ding · 2026
Read Baseline versus cumulative cholesterol, high-density lipoprotein, and glucose index and stroke risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: evidence from the CHARLS study by Chen Chen, Xiao Yang, Cheng Li, Qiqi Xi, Yi Ding (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13419057.txt.
Description
Chen and colleagues examined in 2026 a blood index and stroke risk in people with cardio-kidney-metabolic syndrome. The CHG index combines cholesterol, protective HDL cholesterol, and glucose from routine blood tests. Using a Chinese ageing cohort, the team compared a single baseline index with cumulative exposure over time in 4,661 people at early syndrome stages.
About one in ten participants had a stroke during follow-up. Both the baseline index and the cumulative index were independently tied to higher stroke risk after adjustments. People in the highest third of either measure had roughly a third higher risk than those in the lowest third. The link varied somewhat by sex and drinking status. The authors propose the cheap index as a first-pass screen to flag people needing fuller stroke risk checks.
Catalog record
| CREATOR | Chen Chen, Xiao Yang, Cheng Li, Qiqi Xi, Yi Ding |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |