Cardiovascular disease risk factors in women with O-desmethylangolensin producing and non-producing gut microbial metabotypes: an observational study
Holly Childs, Cara L Frankenfeld, Allyson Dailey, Robin Couch, Margaret Slavin · 2026
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Description
Holly Childs and colleagues studied soy metabolism and heart risk in 148 midlife American women in 2026, using data from the Study of Women's Health Across the Nation. Gut bacteria convert soy daidzein into O-desmethylangolensin in some women only, splitting them into producer and non-producer types with possibly different heart profiles.
Non-producers averaged 7.6 points higher systolic blood pressure than high producers after adjustment, with fasting glucose also trending higher. The paper supports checking gut metabotype when judging soy's heart effects, while noting the small non-producer group of 23 women.
Catalog record
| CREATOR | Holly Childs, Cara L Frankenfeld, Allyson Dailey, Robin Couch, Margaret Slavin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |