Scientific Opinion on waiving of the dog studies in the regulatory process of agrochemicals approval
EFSA Panel on Plant Protection Products and their Residues (PPR), Tamara Coja, Pauline Adriaanse, Antonio Finizio, Maeva Giraudo, Thomas Kuhl, Emily McVey, Francesca Metruccio, Martin Paparella, Silvia Pieper, Eugenio Scanziani, Ivana Teodorovic, Paul Van der Brink, Martin Wilks, Antonio Hernandez‐Jerez, Olavi Pelkonen, Andrea Terron, Jochem Louisse, Martina Panzarea, Adriana Scattareggia Marchese, Judy Choi · 2026
Read Scientific Opinion on waiving of the dog studies in the regulatory process of agrochemicals approval by EFSA Panel on Plant Protection Products and their Residues (PPR), Tamara Coja, Pauline Adriaanse, Antonio Finizio, Maeva Giraudo, Thomas Kuhl, Emily McVey, Francesca Metruccio, Martin Paparella, Silvia Pieper, Eugenio Scanziani, Ivana Teodorovic, Paul Van der Brink, Martin Wilks, Antonio Hernandez‐Jerez, Olavi Pelkonen, Andrea Terron, Jochem Louisse, Martina Panzarea, Adriana Scattareggia Marchese, Judy Choi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13417730.txt.
Description
The EFSA PPR Panel weighs whether routine dog toxicity studies can be waived in pesticide approval, in a 2026 scientific opinion. European rules require 90 day feeding studies in rats and dogs for new active substances. The dog study's added value has been questioned, prompting a retrospective review by the panel.
Across past cases, nearly all species differences in safe dose levels traced to study design, natural variation, or body size scaling, not true dog sensitivity. A tiered strategy with set data criteria is proposed to justify waivers case by case. The approach also promotes non animal methods in safety testing.
Catalog record
| CREATOR | EFSA Panel on Plant Protection Products and their Residues (PPR), Tamara Coja, Pauline Adriaanse, Antonio Finizio, Maeva Giraudo, Thomas Kuhl, Emily McVey, Francesca Metruccio, Martin Paparella, Silvia Pieper, Eugenio Scanziani, Ivana Teodorovic, Paul Van der Brink, Martin Wilks, Antonio Hernandez‐Jerez, Olavi Pelkonen, Andrea Terron, Jochem Louisse, Martina Panzarea, Adriana Scattareggia Marchese, Judy Choi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 175 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |