Haemolytic Anaemia; Beyond Sickle Cell Anaemia: A Case Series of Patients With Paroxysmal Nocturnal Haemoglobinuria in Kenya
Matilda Ong’ondi, Otom Lavender, Muraya Gathinji, Zaheer Bagha · 2026
Read Haemolytic Anaemia; Beyond Sickle Cell Anaemia: A Case Series of Patients With Paroxysmal Nocturnal Haemoglobinuria in Kenya by Matilda Ong’ondi, Otom Lavender, Muraya Gathinji, Zaheer Bagha (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13417713.txt.
Description
Matilda Ong'ondi and colleagues describe seven patients in Kenya with paroxysmal nocturnal haemoglobinuria, a rare blood disorder often overshadowed by sickle cell disease, in a 2026 case series. A gene fault strips red cells of shields against the complement system, so cells burst inside vessels. Diagnosis was confirmed by a sensitive flow cytometry test.
Patients were young, aged 17 to 38, mostly male, and all needed repeated transfusions for anaemia. One had severe marrow failure, and another suffered a gut vein clot with bowel damage. Care was mostly supportive because complement blocking drugs were unavailable. One patient received a successful sibling stem cell transplant.
Catalog record
| CREATOR | Matilda Ong’ondi, Otom Lavender, Muraya Gathinji, Zaheer Bagha |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |