Systemic Immune‐Inflammation Index and Gait Speed in Older Adults: Evidence From NHANES 1999–2002
Ying‐Lun Chen, Zhen‐Xuan Ma · 2026
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Description
Ying-Lun Chen and Zhen-Xuan Ma write a 2026 letter on inflammation and walking speed in older adults, using United States survey data from 1999 to 2002. Their marker, the systemic immune inflammation index, combines platelet, neutrophil, and lymphocyte counts. Participants were 2,007 community living adults aged 60 or older, with gait measured over a 20 foot walk.
Higher index values linked to slower walking after wide adjustment, most clearly in men. People in the top quarter walked notably slower than those in the bottom quarter. Muscle pathways helped explain the link: leg strength accounted for about a third of the effect, and calf size for a smaller share.
Catalog record
| CREATOR | Ying‐Lun Chen, Zhen‐Xuan Ma |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 7 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |