Host-Directed Antiviral Strategies Against Influenza Viruses: Host Targets, Multi-Omics Approaches and AI-Assisted Discovery
Xianfeng Hui, Shihuan Ding, Shuoxiang Gao, Shuochen Xu, Tiesuo Zhao, Xiaowei Tian, Hui Wang · 2026
Read Host-Directed Antiviral Strategies Against Influenza Viruses: Host Targets, Multi-Omics Approaches and AI-Assisted Discovery by Xianfeng Hui, Shihuan Ding, Shuoxiang Gao, Shuochen Xu, Tiesuo Zhao, Xiaowei Tian, Hui Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13417260.txt.
Description
Xianfeng Hui and co-authors review strategies that attack flu by targeting the host rather than the virus, in a 2026 article. Flu viruses mutate fast and often resist drugs aimed at their own proteins. Host factors, the cell machinery viruses borrow to copy themselves, change far more slowly and could offer steadier targets.
Large scale omics studies, which measure genes, proteins, and metabolites together, now reveal many such host factors. Artificial intelligence helps sift those lists for drug ready candidates. The review gathers known targets and shows how these tools speed discovery. Benefits could span human and animal flu, though safety testing in people remains ahead.
Catalog record
| CREATOR | Xianfeng Hui, Shihuan Ding, Shuoxiang Gao, Shuochen Xu, Tiesuo Zhao, Xiaowei Tian, Hui Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 89822 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |