Bazi Bushen Capsule restores fertility by targeting mitochondrial health in aging endometrium

Shangqi Li, Feng Deng, Hongjuan Niu, Meng Li, Zeyang Lin, Jiayi Ma, Yue Wang, Yueqi Leng, Yunlong Hou, Wenwen Cui, Yang Yu, Heng Pan, Ping Zhou, Rong Li · 2026

Read Bazi Bushen Capsule restores fertility by targeting mitochondrial health in aging endometrium by Shangqi Li, Feng Deng, Hongjuan Niu, Meng Li, Zeyang Lin, Jiayi Ma, Yue Wang, Yueqi Leng, Yunlong Hou, Wenwen Cui, Yang Yu, Heng Pan, Ping Zhou, Rong Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13416912.txt.

Description

Li and colleagues report a 2026 study of a herbal capsule called Bazi Bushen and its effect on the aging womb lining. With age the lining responds less well to pregnancy signals, and good treatments are scarce. The team tested the capsule in naturally aged mice and in aged human womb-lining cells, using gene-readout tools and computer models of its ingredients.

The capsule improved how well the lining received an embryo and how its cells changed to support early pregnancy. It acted through a cell energy pathway, AMPK and SIRT3, that guards mitochondria, the cell's power units. One ingredient, luteolin, stood out: it helped clear worn mitochondria and curbed a protein that splits them apart. Other named ingredients included several ginseng compounds. If it holds in women, it could raise fertility chances for older mothers.

Catalog record

CREATORShangqi Li, Feng Deng, Hongjuan Niu, Meng Li, Zeyang Lin, Jiayi Ma, Yue Wang, Yueqi Leng, Yunlong Hou, Wenwen Cui, Yang Yu, Heng Pan, Ping Zhou, Rong Li
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE71 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13416912

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