ViraLite: an ultracompact HIV viral load self-testing system with internal quality control
Aneesh Kshirsagar, Anthony J Politza, Tianyi Liu, Md Ahasan Ahamed, Ming Dong, Muhammad Asad Ullah Khalid, Roland Jones, Uttara Seshu, Kathryn Risher, Casey N Pinto, Yusheng Zhu, Samir K Gupta, Weihua Guan · 2026
Read ViraLite: an ultracompact HIV viral load self-testing system with internal quality control by Aneesh Kshirsagar, Anthony J Politza, Tianyi Liu, Md Ahasan Ahamed, Ming Dong, Muhammad Asad Ullah Khalid, Roland Jones, Uttara Seshu, Kathryn Risher, Casey N Pinto, Yusheng Zhu, Samir K Gupta, Weihua Guan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13415889.txt.
Description
Aneesh Kshirsagar and a large team present ViraLite, a pocket sized HIV viral load self test with a built in sanity check, in 2026. Effective therapy keeps HIV suppressed, yet clinic based load testing is hard to reach for many. Their battery powered device amplifies viral RNA at constant temperature and reads fluorescence with machine learning help, guided by a smartphone.
A human control gene, RNase P, verifies each run worked. That control flagged seventeen of forty-five archived plasma tests as inconclusive rather than falsely negative. Among valid tests, sensitivity reached about 93 percent with perfect specificity against the standard laboratory method.
Catalog record
| CREATOR | Aneesh Kshirsagar, Anthony J Politza, Tianyi Liu, Md Ahasan Ahamed, Ming Dong, Muhammad Asad Ullah Khalid, Roland Jones, Uttara Seshu, Kathryn Risher, Casey N Pinto, Yusheng Zhu, Samir K Gupta, Weihua Guan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |