Liver-on-Chip: An Analysis of Liver Cell Types, Seeding Parameters, and Liver Function Assays
Tenzin Choden Gyeltshen, Dimple Sajin, Hang Thu Ta · 2026
Read Liver-on-Chip: An Analysis of Liver Cell Types, Seeding Parameters, and Liver Function Assays by Tenzin Choden Gyeltshen, Dimple Sajin, Hang Thu Ta (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13413524.txt.
Description
Tenzin Choden Gyeltshen, Dimple Sajin, and Hang Thu Ta sift in 2026 through published liver-on-a-chip systems to find the settings that recur most often. These microfluidic devices aim to replace flat cell cultures and animal tests for drug screening, yet every lab builds them differently, which hampers comparison. The analysis catalogued cell sources, seeding densities, scaffold materials, and the assays used to prove the mini-livers work.
Immortalized HepG2 cells dominate current platforms by a wide margin in the literature surveyed. Typical seeding runs near three million cells per millilitre for flat systems, with lower ranges in three-dimensional builds. Collagen I, alone or blended with Matrigel, is the commonest scaffold, and albumin plus urea serve as the trusted function checks. Benchmarks for builders close the paper.
Catalog record
| CREATOR | Tenzin Choden Gyeltshen, Dimple Sajin, Hang Thu Ta |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 82901 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |