Antibiotic Class-Specific Effects on Inflammatory Bowel Disease: Microbiome Disruption, Risk, and Recovery
Bhargavi Rajarathinam, Pranav V. Nair, Neeraja Murali, Ganga Lekshmi, Abitha K. Sajeev, Archa B. Pillai, Anita Thomas, Sreetha Hely, Kalyani Arun, Vidhya Prakash, Bipin G. Nair, Parvathy Venugopal, Rajaguru Aradhya · 2026
Read Antibiotic Class-Specific Effects on Inflammatory Bowel Disease: Microbiome Disruption, Risk, and Recovery by Bhargavi Rajarathinam, Pranav V. Nair, Neeraja Murali, Ganga Lekshmi, Abitha K. Sajeev, Archa B. Pillai, Anita Thomas, Sreetha Hely, Kalyani Arun, Vidhya Prakash, Bipin G. Nair, Parvathy Venugopal, Rajaguru Aradhya (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13411749.txt.
Description
Bhargavi Rajarathinam leads a team reviewing in 2026 how antibiotic classes differ in their power to stir up inflammatory bowel disease. Crohn's disease and ulcerative colitis arise from genes, immunity, environment, and gut microbes in tangled ways. Antibiotics, which bulldoze microbe communities, stand out among environmental suspects.
Risk tracked the drug class, total exposure, age at exposure, and how many microbe kinds a drug kills. Broad-spectrum and anaerobe-killing drugs showed the strongest links to later disease. Damage runs through lost helpful bacteria, skewed microbial chemistry, and a leakier gut wall. Counter-moves surveyed include careful prescribing, stool transplants, and tailored diets. Matching antibiotic choice to microbiome cost is the authors' central plea.
Catalog record
| CREATOR | Bhargavi Rajarathinam, Pranav V. Nair, Neeraja Murali, Ganga Lekshmi, Abitha K. Sajeev, Archa B. Pillai, Anita Thomas, Sreetha Hely, Kalyani Arun, Vidhya Prakash, Bipin G. Nair, Parvathy Venugopal, Rajaguru Aradhya |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 82060 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |