A Complex Case of Behçet’s Disease With Severe Genital Ulceration: Diagnostic Challenges
Byung C Ji, Thanda Aung, Chandra Smart, Yaqoot Khan · 2026
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Description
Byung C. Ji and colleagues present in 2026 a hard Behçet's disease case: a 36-year-old man whose first flare arrived with severe, tissue-destroying genital ulcers. The syndrome causes recurring mouth and genital sores plus inflammation across skin, eyes, vessels, and gut. No single lab test proves it, which makes early cases treacherous.
Tests for infection, including a broad DNA hunt in plasma, came back negative, and the classic gene marker was absent. Skin biopsy proved decisive: inflammation wrapped the full skin depth with true vessel wall damage, a feature that separates Behçet's from its closest mimic. Formal criteria scored him well past the threshold. High-dose steroids plus colchicine brought full remission in nine weeks.
Catalog record
| CREATOR | Byung C Ji, Thanda Aung, Chandra Smart, Yaqoot Khan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19211 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |