Cortico-retinal decoupling in anisometropic amblyopia: OCTA-VEP multimodal biomarkers reveal neurovascular mismatch patterns

Xindan Meng, Qing Wang, Yixia Zhang · 2026

Read Cortico-retinal decoupling in anisometropic amblyopia: OCTA-VEP multimodal biomarkers reveal neurovascular mismatch patterns by Xindan Meng, Qing Wang, Yixia Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13410861.txt.

Description

Xindan Meng, Qing Wang, and Yixia Zhang report in 2026 a mismatch between blood flow and nerve signals in children with lazy eye from unequal focusing power. One eye sees poorly because the two eyes need very different lenses. Brain effects are known, yet retinal blood flow changes were less clear.

Sixty-eight untreated children aged 4 to 14 had the weaker eye compared with its healthy fellow. Scans showed thinner blood flow in the central retina and a wider vessel-free zone in lazy eyes. Electrical tests showed slower, weaker signals traveling from eye to brain. Flow and signal measures moved together, and nerve layer thickness helped predict sight level. Paired eye and brain markers may sharpen tracking.

Catalog record

CREATORXindan Meng, Qing Wang, Yixia Zhang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39949
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13410861

Browse the full library · About the Tower of Babel