Hydrogel-Based Delivery of Ion Channel Modulators for Cancer Therapy: Current Advances and Future Perspectives
Gizem Ozkurnaz Civir, Ilknur Atli, Ozgur Ozay · 2026
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Description
Gizem Ozkurnaz Civir, Ilknur Atli, and Ozgur Ozay review in 2026 the pairing of ion channel drugs with hydrogel delivery systems for cancer treatment. Ion channels govern cell growth, division, and death, and drugs that modulate them can slow tumours. Getting those drugs to the right place, at the right rate, for long enough is the practical problem hydrogels are meant to solve.
The review surveys recent progress on loading channel modulators into water-rich gel networks that release their cargo in a controlled, localised way near tumours. It weighs the pharmacological advantages, such as steadier exposure and targeting, against biocompatibility, stability, and the hurdles still blocking routine clinical use. Readers developing local cancer therapies get a consolidated account of what has been tried and where the approach falls short.
Catalog record
| CREATOR | Gizem Ozkurnaz Civir, Ilknur Atli, Ozgur Ozay |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 94420 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |