Isosorbide dinitrate as an effective adjunct therapy for acute urinary retention: A randomized controlled trial
Salman Soltani, Hamid Reza Ghorbani, Mahmoud Tavakkoli, Fatemeh Sadabadi, Seyyed Parham Ahmadi, Farid Zeinali · 2026
Read Isosorbide dinitrate as an effective adjunct therapy for acute urinary retention: A randomized controlled trial by Salman Soltani, Hamid Reza Ghorbani, Mahmoud Tavakkoli, Fatemeh Sadabadi, Seyyed Parham Ahmadi, Farid Zeinali (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13407321.txt.
Description
Salman Soltani and colleagues report a 2026 randomised trial from an Iranian urology emergency service: could a heart drug placed under the tongue help men void again after a blocked bladder? All 80 men, aged 50 or over, had a first episode of acute urinary retention from an enlarged prostate and received catheter drainage plus standard prostate medicines.
Half also took daily isosorbide dinitrate for 21 days. After catheter removal, half the added-drug group passed the voiding trial, versus 22.5 percent on standard care alone, and leftover urine volumes fell further in the combined group. Prostate marker levels stayed steady and no serious side effects appeared. Adjusted analysis confirmed the added drug independently predicted success, making it a candidate adjunct worth wider testing.
Catalog record
| CREATOR | Salman Soltani, Hamid Reza Ghorbani, Mahmoud Tavakkoli, Fatemeh Sadabadi, Seyyed Parham Ahmadi, Farid Zeinali |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |