From Gram-Negative Neonatal Sepsis to Neurodevelopmental Impairment: A Retrospective Cohort Study in Preterm Infants

Mihaela Zaharie, Marioara Boia, Aniko Manea, Roxana Maria Jeleriu, Mirabela Adina Dima, Ileana Enatescu, Daniela Iacob · 2026

Read From Gram-Negative Neonatal Sepsis to Neurodevelopmental Impairment: A Retrospective Cohort Study in Preterm Infants by Mihaela Zaharie, Marioara Boia, Aniko Manea, Roxana Maria Jeleriu, Mirabela Adina Dima, Ileana Enatescu, Daniela Iacob (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13406810.txt.

Description

Mihaela Zaharie led a 2026 study of preterm babies who developed bloodstream infections caused by Gram-negative bacteria in a specialist newborn unit. The team looked back at cases from 2022 and 2023, covering both infections appearing soon after birth and those starting later.

Later-starting infections were more common, and Klebsiella pneumoniae was the organism found most often. Resistant bacteria were linked to about half the cases, and roughly one baby in four died in hospital. Among survivors checked at 18 to 24 months, about 38 percent showed developmental problems, mostly in language and thinking skills. Being born earlier stood out as the clearest predictor of both death and later impairment, pointing to early treatment and planned follow-up.

Catalog record

CREATORMihaela Zaharie, Marioara Boia, Aniko Manea, Roxana Maria Jeleriu, Mirabela Adina Dima, Ileana Enatescu, Daniela Iacob
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44677
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13406810

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