HbA1c and Cognitive Functioning Across Bipolar Disorder, Recurrent Major Depressive Disorder, and Schizophrenia: Findings from a Non-Diabetic Sample

Ece Buyuksandalyaci Tunc, Serhat Tunc, Murat Ilhan Atagun, Samet Kose · 2026

Read HbA1c and Cognitive Functioning Across Bipolar Disorder, Recurrent Major Depressive Disorder, and Schizophrenia: Findings from a Non-Diabetic Sample by Ece Buyuksandalyaci Tunc, Serhat Tunc, Murat Ilhan Atagun, Samet Kose (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13406456.txt.

Description

Ece Buyuksandalyaci Tunc and colleagues link a blood sugar marker to thinking skills across three psychiatric diagnoses, reporting in 2026 on non-diabetic patients. HbA1c, the standard long-term sugar measure, was compared with test performance in bipolar disorder, recurrent depression and schizophrenia.

The link was strongest in bipolar disorder, where higher HbA1c tracked with worse speed, attention, memory and social thinking even inside the normal sugar range. Depression showed a weaker, narrower pattern, and schizophrenia none, despite that group carrying the highest HbA1c. Antipsychotic dose raised HbA1c and softened the link partly, but did not explain it away. The authors flag sugar control as a possible lever for cognition in mood disorders.

Catalog record

CREATOREce Buyuksandalyaci Tunc, Serhat Tunc, Murat Ilhan Atagun, Samet Kose
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37809
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13406456

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