Pharmacogenomic landscape of a Moroccan cohort: enhancing global diversity and addressing the North African gap
Souad Kartti, Mohammed Walid Chemao-Elfihri, Mohammed Hakmi, Marouane Aherkou, Rachid ElJaoudi, Lahcen Balouch, Elmostafa El Fahime, Lahcen Belyamani, Saber Boutayeb · 2026
Read Pharmacogenomic landscape of a Moroccan cohort: enhancing global diversity and addressing the North African gap by Souad Kartti, Mohammed Walid Chemao-Elfihri, Mohammed Hakmi, Marouane Aherkou, Rachid ElJaoudi, Lahcen Balouch, Elmostafa El Fahime, Lahcen Belyamani, Saber Boutayeb (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13402624.txt.
Description
Souad Kartti and co-authors map the drug-response genes of a Moroccan cohort, in a 2026 study aimed at a gap in global data. How a person responds to many medicines depends on their genes. North African populations are missing from most pharmacogenomic databases, despite wide genetic diversity that can strongly shift drug response and safety.
Whole-genome sequencing of 109 Moroccan individuals found about 129,000 new variants across thousands of candidate genes. In seventeen genes with firm clinical guidance, several common variants stood out, including ones tied to statin handling and blood thinner dose. Immune gene typing added variants linked to bad drug reactions. The data seed precision medicine for the region.
Catalog record
| CREATOR | Souad Kartti, Mohammed Walid Chemao-Elfihri, Mohammed Hakmi, Marouane Aherkou, Rachid ElJaoudi, Lahcen Balouch, Elmostafa El Fahime, Lahcen Belyamani, Saber Boutayeb |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 72 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |