Prognostic Value of Cranial Nerve Invasion in T4‐Stage Nasopharyngeal Carcinoma: A Retrospective Cohort Study With a Median Follow‐Up of 136 Months
Cuidai Zhang, Hui Liu, Xuejia Liu, Yihao Ye, Zeman Cai, Zewei Chen, Qizhi Zheng · 2026
Read Prognostic Value of Cranial Nerve Invasion in T4‐Stage Nasopharyngeal Carcinoma: A Retrospective Cohort Study With a Median Follow‐Up of 136 Months by Cuidai Zhang, Hui Liu, Xuejia Liu, Yihao Ye, Zeman Cai, Zewei Chen, Qizhi Zheng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13401712.txt.
Description
Cuidai Zhang and colleagues followed patients with advanced nasopharyngeal cancer for over a decade to judge whether invasion of the cranial nerves forecasts survival, in a 2026 retrospective study. The cancer sits behind the nose, close to the skull base, so nerve spread is a live concern in stage T4 disease.
At the Cancer Hospital of Shantou University Medical College, 299 patients with non-metastatic T4 disease were tracked for a median of 136 months. Cranial nerve invasion appeared in 159 patients, just over half. Five and ten-year survival ran lower with invasion than without, roughly 61 and 51 percent against 71 and 62 percent. In adjusted analyses, invasion of cranial nerves two and ten mattered for overall survival, while invasion as a whole did not predict local relapse, where prevertebral muscle invasion was the significant factor.
Catalog record
| CREATOR | Cuidai Zhang, Hui Liu, Xuejia Liu, Yihao Ye, Zeman Cai, Zewei Chen, Qizhi Zheng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |