Exploration of extracellular vesicles from porcine endometrial cells for enhancing the development of parthenogenetic embryos
Shao-Yu Peng, Yen Feng, Min-Jung Lin, Shen-Chang Chang, Jung-Wen Huang, Perng-Chih Shen, Kuo-Tai Yang, Chao-Wei Huang, Chih-Jen Chou, Steven W. Shaw · 2026
Read Exploration of extracellular vesicles from porcine endometrial cells for enhancing the development of parthenogenetic embryos by Shao-Yu Peng, Yen Feng, Min-Jung Lin, Shen-Chang Chang, Jung-Wen Huang, Perng-Chih Shen, Kuo-Tai Yang, Chao-Wei Huang, Chih-Jen Chou, Steven W. Shaw (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13400443.txt.
Description
Shao-Yu Peng and colleagues explore, in 2026, tiny parcels released by pig womb cells that may help embryos grow in the laboratory. The parcels, called extracellular vesicles, carry small RNA molecules that can change how cells behave. Lab-grown pig eggs mature and develop less well than those in the body, a problem for breeding and research.
Fluid from the womb cells improved egg maturation. One carried RNA, miR-21-5p, raised the rate at which artificially activated eggs reached the blastocyst stage, acting by lowering a brake gene and raising a key embryo gene. Another RNA lifted early cell division rates. The work points to natural signals that could make lab embryo production more efficient.
Catalog record
| CREATOR | Shao-Yu Peng, Yen Feng, Min-Jung Lin, Shen-Chang Chang, Jung-Wen Huang, Perng-Chih Shen, Kuo-Tai Yang, Chao-Wei Huang, Chih-Jen Chou, Steven W. Shaw |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46542 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |