Integrating condensates into protein lifespan – From birth to death
Chloe A. Langridge, Emily M. Sontag · 2026
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Description
Chloe A Langridge and Emily M Sontag review, in 2026, how droplet-like cell compartments called condensates act across the whole life of a protein. Cells keep protein quality in balance from gene reading through folding to disposal. Condensates gather molecules without a membrane and can speed or pause these steps.
Some condensates help control which genes are read or which messages get translated. Others hold misfolded proteins aside or aid their breakdown. Under stress, new condensates form and old ones change how they behave. The authors pull together what is known in calm and stressed cells, arguing that grasping these shifts will help explain how protein control fails in disease.
Catalog record
| CREATOR | Chloe A. Langridge, Emily M. Sontag |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48949 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |