Integrated multi-omic analyses reveal novel gene–metabolite relationships in human steatohepatitic hepatocellular carcinoma
Garrett B Anspach, Robert M Flight, Sehyung Park, Daheng He, Chi Wang, Hunter NB Moseley, Robert N Helsley · 2026
Read Integrated multi-omic analyses reveal novel gene–metabolite relationships in human steatohepatitic hepatocellular carcinoma by Garrett B Anspach, Robert M Flight, Sehyung Park, Daheng He, Chi Wang, Hunter NB Moseley, Robert N Helsley (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13400273.txt.
Description
Garrett B Anspach and colleagues combine several kinds of molecular data in a 2026 study of a fatty type of liver cancer. They used paired tumor and nearby non-tumor tissue from eight patients treated in Kentucky. Fatty liver disease linked to metabolism is now a fast-growing cause of this cancer.
Lab tests measured genes, small molecules and fats in each sample, then merged the results. Tumors held more fat droplets and signs of inflammation, with shifts in over 1,600 genes and a similar number of small molecules. The team also found 303 new links between gene activity and specific molecules, and checked gene patterns in 424 samples from a cancer atlas.
Catalog record
| CREATOR | Garrett B Anspach, Robert M Flight, Sehyung Park, Daheng He, Chi Wang, Hunter NB Moseley, Robert N Helsley |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 79190 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |