Transient Platelet Elevation Following Oseltamivir Administration in Pediatric Chronic Immune Thrombocytopenia
Soh Yamamoto, Yu Furui, Eri Okura, Kenichi Sakamoto, Koichi Hirabayashi, Shoji Saito, Yozo Nakazawa · 2026
Read Transient Platelet Elevation Following Oseltamivir Administration in Pediatric Chronic Immune Thrombocytopenia by Soh Yamamoto, Yu Furui, Eri Okura, Kenichi Sakamoto, Koichi Hirabayashi, Shoji Saito, Yozo Nakazawa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13400131.txt.
Description
Soh Yamamoto and colleagues report three adolescents whose chronically low platelets unexpectedly surged after taking the influenza drug oseltamivir, in a 2026 case series from Japan. Across four influenza episodes, every one treated with oseltamivir, platelet counts climbed sharply about a week and a half after the antiviral started.
The median count rose from 9.1 to 26.7 in units of ten thousand per microliter, peaking at a median of 11.5 days after oseltamivir began. One girl's count overshot to 93.1 in the same units before settling. Two episodes forced the team to cut or pause eltrombopag to avoid excessive clotting risk, and counts drifted back to baseline over a median of 57 days. No thrombosis, major bleeding, or other harm occurred. They advise planned monitoring when children with chronic ITP on eltrombopag receive oseltamivir.
Catalog record
| CREATOR | Soh Yamamoto, Yu Furui, Eri Okura, Kenichi Sakamoto, Koichi Hirabayashi, Shoji Saito, Yozo Nakazawa |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9994 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |