USE OF THE FIBROSIS-4 INDEX FOR SCREENING LIVER FIBROSIS IN PEOPLE LIVING WITH HUMAN IMMUNODEFICIENCY VIRUS AND GLUCOSE METABOLISM DISORDERS
Arthur Cavalcante LOPES, Amanda Aymoré SANTOS, Ivo da Cunha NUNES, Jeremias Estevam LOPES, Rosana Maria Feio LIBONATI · 2026
Read USE OF THE FIBROSIS-4 INDEX FOR SCREENING LIVER FIBROSIS IN PEOPLE LIVING WITH HUMAN IMMUNODEFICIENCY VIRUS AND GLUCOSE METABOLISM DISORDERS by Arthur Cavalcante LOPES, Amanda Aymoré SANTOS, Ivo da Cunha NUNES, Jeremias Estevam LOPES, Rosana Maria Feio LIBONATI (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13399932.txt.
Description
Arthur Cavalcante Lopes and colleagues tested the FIB-4 score as a liver fibrosis screen in people living with HIV who also have diabetes or prediabetes. The work is a 2026 study from a tropical medicine center in Belém, Brazil. The team enrolled 100 patients on continuous antiretroviral therapy between March and November 2025 and combined the score with ultrasound imaging and metabolic measurements.
FIB-4 came back altered in 32 of the 100 participants, with no difference between men and women. Ultrasound showed mild fatty liver in 47.0 percent and clinically significant steatosis in 11.0 percent. The score's weakness showed in classification: it did not adequately pick out the significant steatosis cases. The authors recommend FIB-4 for what it does well, ruling out advanced fibrosis, while pairing it with metabolic assessment. Anyone at or above a score of 1.3 should go for elastography rather than trusting the index alone.
Catalog record
| CREATOR | Arthur Cavalcante LOPES, Amanda Aymoré SANTOS, Ivo da Cunha NUNES, Jeremias Estevam LOPES, Rosana Maria Feio LIBONATI |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |