Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3
Wen‐Ke Yin, Xue‐Mei Xie, Xiao‐Yan Song, Yue Xiang · 2026
Read Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3 by Wen‐Ke Yin, Xue‐Mei Xie, Xiao‐Yan Song, Yue Xiang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13399867.txt.
Description
Wen-Ke Yin, Xue-Mei Xie, Xiao-Yan Song, and Yue Xiang study why stomach cancer cells resist a common drug, in work dated 2026. The drug cisplatin often stops working over time. Cells can protect themselves by clearing damaged parts, a process that helps them survive treatment.
The team looked at a gene called CREB3L4 and a partner protein it controls. Both were high in drug resistant cells. When CREB3L4 was knocked down, the partner fell, cell self clearing dropped, and drug resistance eased. The results point to a chain that could be a target for new care.
Catalog record
| CREATOR | Wen‐Ke Yin, Xue‐Mei Xie, Xiao‐Yan Song, Yue Xiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |