Ultrasound‐Guided Thoracic Paravertebral Block With Liposomal Versus Standard Bupivacaine for Older Patients After Thoracoscopic Surgery
Wen‐Cheng Shi, Ying‐Jie Tang, Yao Wang, Zhong Zheng, Jing He · 2026
Read Ultrasound‐Guided Thoracic Paravertebral Block With Liposomal Versus Standard Bupivacaine for Older Patients After Thoracoscopic Surgery by Wen‐Cheng Shi, Ying‐Jie Tang, Yao Wang, Zhong Zheng, Jing He (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13399631.txt.
Description
Wen-Cheng Shi and colleagues compared two forms of bupivacaine for a chest-wall nerve block in older patients having keyhole lung surgery, in a 2026 randomized trial. Liposomal bupivacaine packages the same drug in tiny fat bubbles that release it over up to three days. The team tested whether it eases pain and opioid use after video-assisted thoracoscopic surgery.
A total of 116 older patients were allocated to standard or liposomal bupivacaine, with the block placed before anesthesia began. Pain scores matched at most time points but ran significantly lower in the liposomal group at 24 and 36 hours after surgery. That group scored higher on the QoR-15 recovery questionnaire at 24 hours, pressed the pump fewer times, and used less sufentanil between 24 and 72 hours. Rates of side effects and postoperative delirium did not differ. The authors say the long-acting form buys a real, if time-limited, advantage for this age group.
Catalog record
| CREATOR | Wen‐Cheng Shi, Ying‐Jie Tang, Yao Wang, Zhong Zheng, Jing He |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29297 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |