Dexmedetomidine versus magnesium sulphate as adjuvants to ropivacaine in ilioinguinal–iliohypogastric nerve block for inguinal hernia repair: A randomised controlled trial
Laxman K. Senapati, Reddi Gireesh Bodigandla, Amit Pradhan, Rajendra K. Sahoo, Priyadarsini Samanta · 2026
Read Dexmedetomidine versus magnesium sulphate as adjuvants to ropivacaine in ilioinguinal–iliohypogastric nerve block for inguinal hernia repair: A randomised controlled trial by Laxman K. Senapati, Reddi Gireesh Bodigandla, Amit Pradhan, Rajendra K. Sahoo, Priyadarsini Samanta (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13399270.txt.
Description
Laxman K. Senapati and colleagues ran a randomized trial comparing two drugs added to a nerve block for hernia surgery pain, reporting in 2026. The ilioinguinal-iliohypogastric block numbs the groin for inguinal hernia repair, yet plain local anesthetic wears off fairly soon. The trial tested whether dexmedetomidine or magnesium sulphate, each mixed with ropivacaine, could stretch pain relief longer.
One hundred twenty patients were assigned to three groups of forty: ropivacaine alone, ropivacaine with magnesium sulphate, or ropivacaine with dexmedetomidine. The dexmedetomidine group waited far longer before needing rescue pain relief, a median difference of about 1080 minutes against the plain group, and used less opioid medicine over the first day. Their pain scores at rest and on movement were also lower at several time points. Sedation ran higher soon after surgery in that group, though breathing problems did not appear. The authors judge dexmedetomidine the better additive.
Catalog record
| CREATOR | Laxman K. Senapati, Reddi Gireesh Bodigandla, Amit Pradhan, Rajendra K. Sahoo, Priyadarsini Samanta |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29361 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |