Successful allo‐hematopoietic stem cell transplantation using washed hematopoietic stem cells in a pediatric patient complicated by acute myeloid leukemia and severe anaphylaxis to blood product
Jieyu Tian, Guanghua Zhu, Maoquan Qin, Chenguang Jia, Shuxuan Ma, Bin Wang, Yanhui Luo · 2026
Read Successful allo‐hematopoietic stem cell transplantation using washed hematopoietic stem cells in a pediatric patient complicated by acute myeloid leukemia and severe anaphylaxis to blood product by Jieyu Tian, Guanghua Zhu, Maoquan Qin, Chenguang Jia, Shuxuan Ma, Bin Wang, Yanhui Luo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13398660.txt.
Description
Jieyu Tian and co-authors tell how washed donor stem cells carried a child through transplant despite life-threatening allergies to blood products. Their 2026 letter describes a girl treated for ulcerative colitis from age ten who developed high-risk acute myeloid leukaemia at fifteen. Transfusions, the backbone of transplant care, triggered anaphylactic shock in her, traced mainly to plasma proteins.
Her sister donated matched stem cells. The team washed the graft twice in saline with a little of the patient's own plasma. The wash lost about 23 percent of cells yet kept counts well above engraftment needs. The infusion passed safely, blood counts recovered by day 12, and follow-up showed full donor marrow with leukaemia gone. Washed platelets later also transfused without incident.
Catalog record
| CREATOR | Jieyu Tian, Guanghua Zhu, Maoquan Qin, Chenguang Jia, Shuxuan Ma, Bin Wang, Yanhui Luo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 10285 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |