Distinct pregnancy challenges in PCOS women undergoing IVF/ICSI with singleton and twin births: a propensity-matched analysis
Zhekun Zhao, Minyue Tang, Shan Wan, Sisi Wang, Bingbin Xu, Yimin Zhu · 2026
Read Distinct pregnancy challenges in PCOS women undergoing IVF/ICSI with singleton and twin births: a propensity-matched analysis by Zhekun Zhao, Minyue Tang, Shan Wan, Sisi Wang, Bingbin Xu, Yimin Zhu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13397808.txt.
Description
Zhekun Zhao and colleagues separated singleton and twin births to clarify pregnancy risks for women with polycystic ovary syndrome, or PCOS, using fertility treatment. Their 2026 analysis covers women who reached at least 20 weeks after IVF or ICSI, a lab method that injects a single sperm into an egg. Earlier studies mixed single and multiple births, which may explain conflicting results on PCOS pregnancy outcomes.
Matching patients from 95 hospitals, the team compared 696 PCOS singleton cases with 1,392 controls, plus 201 twin cases with 402 controls. Singleton PCOS pregnancies carried higher odds of high blood pressure disorders, pre-eclampsia, and cervical weakness, while twin PCOS pregnancies carried higher odds of gestational diabetes and very preterm birth. The paper gives clinicians birth-number-specific risks to guide monitoring, while noting that matching cannot remove every source of bias.
Catalog record
| CREATOR | Zhekun Zhao, Minyue Tang, Shan Wan, Sisi Wang, Bingbin Xu, Yimin Zhu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |