Oral squamous cell carcinoma is associated with altered salivary microbiome structure and reduced community evenness
Miguel Ferriz-Jordán, David Hervás, Leticia Bagan, Concepción Gimeno, Alejandro Herreros-Pomares, José Bagán · 2026
Read Oral squamous cell carcinoma is associated with altered salivary microbiome structure and reduced community evenness by Miguel Ferriz-Jordán, David Hervás, Leticia Bagan, Concepción Gimeno, Alejandro Herreros-Pomares, José Bagán (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13396630.txt.
Description
Miguel Ferriz-Jordán and five co-authors published a 2026 study of the saliva microbiome in oral cancer. Oral squamous cell carcinoma is a major global burden, and spit is easy to collect, so its microbes may serve as early markers. The team sequenced bacterial genes from saliva of 113 people: 52 patients with the cancer and 61 healthy controls. They compared the communities with several statistical methods.
The cancer group's saliva held a differently structured community with less even spread among species, though the total count of species held steady. Several bacterial groups ran high in the cancer group, while one ran low. The authors describe the pattern as a reshaping, not a collapse, of the mouth's ecology. They stress the candidate markers need testing in larger, longer studies before any clinical use.
Catalog record
| CREATOR | Miguel Ferriz-Jordán, David Hervás, Leticia Bagan, Concepción Gimeno, Alejandro Herreros-Pomares, José Bagán |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |