Tryptanthrin Nanoliposomal Lotion as a Corticosteroid-Free Strategy for Safe and Effective Treatment of Atopic Dermatitis

Yo Han Song, Young-Guk Na, Moon Sup Yoon, Da-Eun Kim, Suyeon Hwang, Samuel Lee, Young Ju Jo, Ji Hyun Bang, Gabsik Yang, Dong-Sung Lee, Hong-Ki Lee, Cheong-Weon Cho · 2026

Read Tryptanthrin Nanoliposomal Lotion as a Corticosteroid-Free Strategy for Safe and Effective Treatment of Atopic Dermatitis by Yo Han Song, Young-Guk Na, Moon Sup Yoon, Da-Eun Kim, Suyeon Hwang, Samuel Lee, Young Ju Jo, Ji Hyun Bang, Gabsik Yang, Dong-Sung Lee, Hong-Ki Lee, Cheong-Weon Cho (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13396491.txt.

Description

Yo Han Song and co-authors made a steroid-free lotion for eczema-prone skin out of a plant compound sealed inside tiny fat bubbles. Their 2026 study targets atopic dermatitis, the itchy, relapsing skin disease usually managed with steroid creams whose side effects limit long use.

The active compound, tryptanthrin, barely dissolves in water, so little of it crosses the skin when used plain. Loading it into liposomes, small spheres of fat, improved its stability, the lotion's moisturizing feel, and how steadily the drug released. Tests then moved to human skin cells in the lab, the first step in judging whether the formula calms inflamed skin safely.

Catalog record

CREATORYo Han Song, Young-Guk Na, Moon Sup Yoon, Da-Eun Kim, Suyeon Hwang, Samuel Lee, Young Ju Jo, Ji Hyun Bang, Gabsik Yang, Dong-Sung Lee, Hong-Ki Lee, Cheong-Weon Cho
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE75554
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13396491

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