Summary of Research: Cognition and Employment Status of People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Two-Year CLARIFY-MS Study
Bruno Brochet, Dawn Langdon, Eva Kubala Havrdova, Jeanette Lechner-Scott, Xavier Montalban, Francesco Patti, Alessandra Solari, Nektaria Alexandri, Annette Lehn, Andrzej Smyk, Krzysztof Selmaj · 2026
Read Summary of Research: Cognition and Employment Status of People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Two-Year CLARIFY-MS Study by Bruno Brochet, Dawn Langdon, Eva Kubala Havrdova, Jeanette Lechner-Scott, Xavier Montalban, Francesco Patti, Alessandra Solari, Nektaria Alexandri, Annette Lehn, Andrzej Smyk, Krzysztof Selmaj (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13396065.txt.
Description
Bruno Brochet and a large study team summarize two years of results on thinking skills and work in people with highly active relapsing multiple sclerosis treated with cladribine tablets. The 2026 summary covers the CLARIFY-MS study, an open-label phase 4 trial with no comparison group.
Of 482 people who took at least one dose, 399 completed a standard battery of thinking tests at the start and at 12 and 24 months. Scores held steady overall, and most people kept or improved their processing speed by margins doctors count as meaningful. Employment also stayed stable, with more than 40 percent in full-time work, even through the COVID-19 pandemic years covered by the trial.
Catalog record
| CREATOR | Bruno Brochet, Dawn Langdon, Eva Kubala Havrdova, Jeanette Lechner-Scott, Xavier Montalban, Francesco Patti, Alessandra Solari, Nektaria Alexandri, Annette Lehn, Andrzej Smyk, Krzysztof Selmaj |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2671 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |