GH Stimulation testing is unnecessary in patients with hypothalamic–pituitary disease, preserved pituitary function, and IGF-I SDS ≥ 0
Valentina Gasco, Daniela Cuboni, Michela Sibilla, Francesca Mocellini, Alice Martinotti, Davide Lucisano, Ezio Ghigo, Gianluca Aimaretti, Silvia Grottoli, Mauro Maccario · 2026
Read GH Stimulation testing is unnecessary in patients with hypothalamic–pituitary disease, preserved pituitary function, and IGF-I SDS ≥ 0 by Valentina Gasco, Daniela Cuboni, Michela Sibilla, Francesca Mocellini, Alice Martinotti, Davide Lucisano, Ezio Ghigo, Gianluca Aimaretti, Silvia Grottoli, Mauro Maccario (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13395983.txt.
Description
Valentina Gasco and co-authors tackle a testing shortcut in hormone care in their 2026 study: when can doctors safely skip the stimulation test used to prove growth hormone deficiency in adults? Such tests are standard, yet they are costly, slow, and known to mislead.
The group focused on adults with disease of the hypothalamus or pituitary who had no other hormone losses. For this group they built a probability model based on IGF-I levels, a blood marker tied to growth hormone action, drawing the inputs from published data. The aim was a rule that flags patients whose chance of deficiency is so low that dynamic testing adds nothing.
Catalog record
| CREATOR | Valentina Gasco, Daniela Cuboni, Michela Sibilla, Francesca Mocellini, Alice Martinotti, Davide Lucisano, Ezio Ghigo, Gianluca Aimaretti, Silvia Grottoli, Mauro Maccario |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37615 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |