The New Spine of Access to the Brain’s Secrets: Extracellular Vesicles from Cerebrospinal Fluid Liquid Biopsies in CNS Diseases and Blood–Brain Barrier Research
Isabeau Vermeulen, Yannick Parmentier, Jill Barber, Arnaud François, Loubna Chadli, Nicolas Provost, Emre M. Isin, Kayode Ogungbenro, Aleksandra Galetin, Amin Rostami-Hodjegan, Zubida M. Al-Majdoub · 2026
Read The New Spine of Access to the Brain’s Secrets: Extracellular Vesicles from Cerebrospinal Fluid Liquid Biopsies in CNS Diseases and Blood–Brain Barrier Research by Isabeau Vermeulen, Yannick Parmentier, Jill Barber, Arnaud François, Loubna Chadli, Nicolas Provost, Emre M. Isin, Kayode Ogungbenro, Aleksandra Galetin, Amin Rostami-Hodjegan, Zubida M. Al-Majdoub (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13395934.txt.
Description
Isabeau Vermeulen and co-authors wrote a 2026 review on tiny particles called extracellular vesicles that brain cells shed into cerebrospinal fluid, the liquid that bathes the brain and spine. Because these vesicles carry proteins, nucleic acids, and fats from the cells that made them, they may reveal brain disease without a tissue biopsy.
Vesicles from spinal fluid sit closer to the brain than those in blood, so their signals are less diluted by the rest of the body. The review weighs that promise against low yields, purity problems, and the lack of shared isolation methods. It argues that standard steps plus combined molecular profiling could turn these vesicles into useful tests for disorders of the central nervous system.
Catalog record
| CREATOR | Isabeau Vermeulen, Yannick Parmentier, Jill Barber, Arnaud François, Loubna Chadli, Nicolas Provost, Emre M. Isin, Kayode Ogungbenro, Aleksandra Galetin, Amin Rostami-Hodjegan, Zubida M. Al-Majdoub |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 72198 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |