The interplay between pulsatility, sympathetic regulation and renal physiology: Implications for left ventricular assist devices
Tania Warnakulasuriya, Zaid Bahi, Rohit Ramchandra · 2026
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Description
Tania Warnakulasuriya, Zaid Bahi, and Rohit Ramchandra review, in 2026, how steady pump flow may affect kidneys in heart failure care. Heart pumps called LVADs keep blood moving, but many give smooth flow instead of the natural pulse. Pulse loss can shift nerve signals that raise stress activity and can change nitric oxide release. The review asks what that means for kidney work.
Pulsed flow seems to calm stress nerve activity in lab and clinic reports. Proof that kidneys then work better is weak, though. Most studies were small, looked back at old data, and used rough kidney measures. The authors call for sharper tests of kidney parts in future work.
Catalog record
| CREATOR | Tania Warnakulasuriya, Zaid Bahi, Rohit Ramchandra |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38070 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |