Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection
Zifan Li, Yu Kang, Yuyu Niu · 2026
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Description
Zifan Li, Yu Kang, and Yuyu Niu reviewed stem cell therapies for type 1 diabetes in 2026. In this disease the body loses the cells that make insulin. Lab-grown insulin cells, made from stem cells that can become many cell types, offer a possible root treatment.
Guides based on how the pancreas forms in the womb now let labs make mature insulin cells that act much like real ones. Transplants reversed high blood sugar in mice and primates, and early human trials found the approach safe, with some patients free of insulin shots. Hard problems remain: cell maturity, mixed cell types, batch variation, large-scale making, and immune rejection even with a patient's own cells.
Catalog record
| CREATOR | Zifan Li, Yu Kang, Yuyu Niu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |