Systematic Review and Meta‐Analysis on the Efficacy and Safety of Salvage Esophagectomy for T4 Esophageal Squamous Cell Carcinoma

Makoto Sakai, Kengo Kuriyama, Kazue Nagai, Ken Shirabe, Hiroshi Saeki · 2026

Read Systematic Review and Meta‐Analysis on the Efficacy and Safety of Salvage Esophagectomy for T4 Esophageal Squamous Cell Carcinoma by Makoto Sakai, Kengo Kuriyama, Kazue Nagai, Ken Shirabe, Hiroshi Saeki (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13394042.txt.

Description

Makoto Sakai, Kengo Kuriyama, Kazue Nagai, Ken Shirabe, and Hiroshi Saeki review salvage esophagectomy for advanced esophageal cancer, in a 2026 meta-analysis. The operation removes the esophagus after other treatment fails for tumors that invade nearby structures. It carries high complication and death rates.

Eight studies with about two hundred cases were pooled. Major complications affected about thirty percent of patients, and leaks at the surgical join were common at eighteen percent. About seven percent died, while complete tumor removal was achieved in roughly seventy percent. Survival looked better when removal was complete. The authors advise reserving the operation for carefully chosen patients.

Catalog record

CREATORMakoto Sakai, Kengo Kuriyama, Kazue Nagai, Ken Shirabe, Hiroshi Saeki
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13394042

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