Pemphigus vulgaris—a blistering clinical enigma: case report

Anuradha Ganesan, Vinu B Priya, Krithika Chandrasekar Lakshmi, Yesoda Aniyan · 2026

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Description

Anuradha Ganesan, Vinu B Priya, Krithika Chandrasekar Lakshmi, and Yesoda Aniyan present a 35-year-old South Asian man whose month of recurring mouth ulcers announced pemphigus vulgaris. The autoimmune blistering disease can threaten the airway when it spreads through the throat. His skin examination added blisters across chest and back. Antibodies in this disease attack the glue proteins holding skin cells together, and mouth lesions are the opening sign in most patients.

Scrapings from the ulcers showed the rounded, detached cells typical of the condition, and a biopsy with immune studies confirmed the diagnosis. Steroids remain the backbone of treatment despite limited options in some settings, backed by supportive care and steroid-sparing drugs where available. The authors stress that careful tissue and immune work separates this disease from look-alike blistering disorders, and that several specialties must coordinate when the upper airway is involved.

Catalog record

CREATORAnuradha Ganesan, Vinu B Priya, Krithika Chandrasekar Lakshmi, Yesoda Aniyan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30304
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13393874

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