Integrin-binding sialoprotein as an extracellular matrix–associated independent prognostic biomarker in glioma
Wei-wei Chen, Yu-xing Hao, Wen-qing Hong, Qi-you Yuan, Hao-dong Jin, Jin Peng, Ming Shan, Cheng-cong Li · 2026
Read Integrin-binding sialoprotein as an extracellular matrix–associated independent prognostic biomarker in glioma by Wei-wei Chen, Yu-xing Hao, Wen-qing Hong, Qi-you Yuan, Hao-dong Jin, Jin Peng, Ming Shan, Cheng-cong Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13393847.txt.
Description
Wei-wei Chen and colleagues evaluate integrin-binding sialoprotein as a glioma prognosis marker in a 2026 study. This bone-related protein has been tied to metastasis in breast, lung, and prostate cancers, but its role in brain glioma was poorly characterized.
Gene data from Chinese glioma databases were linked to clinical features, with Cox models testing prognostic value and staining used to confirm expression. Pathway analysis connected high IBSP levels to adverse biology, and drug screens suggested agents that might target it. Neuro-oncologists gain a candidate marker for stratifying glioma risk.
Catalog record
| CREATOR | Wei-wei Chen, Yu-xing Hao, Wen-qing Hong, Qi-you Yuan, Hao-dong Jin, Jin Peng, Ming Shan, Cheng-cong Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |