GLP‐1 Receptor Agonists and Endoscopy: Understanding Gastric Stasis, Aspiration Risk, and Contemporary Peri‐Procedural Guidance

Junaid Beig, Jason Ta, Sophie Jones, Emily Scott, Khalid Sofi, Frances Osler, Marije Jansen, Puneet Chhabra · 2026

Read GLP‐1 Receptor Agonists and Endoscopy: Understanding Gastric Stasis, Aspiration Risk, and Contemporary Peri‐Procedural Guidance by Junaid Beig, Jason Ta, Sophie Jones, Emily Scott, Khalid Sofi, Frances Osler, Marije Jansen, Puneet Chhabra (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13393514.txt.

Description

Junaid Beig and seven colleagues review the endoscopy dilemma created by GLP-1 receptor agonists, the diabetes and weight drugs that slow stomach emptying. More patients now arrive for gut procedures on these medicines, raising fears of leftover food, disrupted sessions, and inhalation of stomach contents under sedation. The review blends mechanism studies, stomach-emptying scans, large cohorts, and global guidance.

Exposure to the drugs again and again raises retained gastric contents and session disruption during upper endoscopy. Whether leftover contents truly cause meaningful inhaling stays uncertain: colonoscopy data show no rise in aspiration pneumonia, and upper scope events remain a small fraction of cases. Current guidance favours continuing the drugs with dietary tweaks, structured risk checks, selective stomach ultrasound, and clear team talk over blanket stopping, with a clear-liquid day beforehand helping further.

Catalog record

CREATORJunaid Beig, Jason Ta, Sophie Jones, Emily Scott, Khalid Sofi, Frances Osler, Marije Jansen, Puneet Chhabra
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE50316
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13393514

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